Spontaneous disinsertion of an iris-fixated 3-piece intraocular lens haptic from the optic in a patient with pathologic myopia

A 39-year-old man with pathologic myopia and a dislocated native lens of the right eye underwent pars plana lensectomy and implantation of an iris-fixated 3-piece MA60MA foldable acrylic intraocular lens with -5.0 diopter power. The patient presented 11 months later with spontaneous haptic disinsertion from the optic. The meniscus (concave-convex) configuration of this iris-fixated lens may have contributed to spontaneous haptic-optic disjunction. This is the first such case reported involving a negative diopter power intraocular lens. Introduction Dislocation of an intraocular lens (IOL) haptic from the optic has been reported to occur during surgery, after trauma, and spontaneously [1,2]. Spontaneous dislocations are rare, with only 8 cases reported in the literature [3-8]. Such cases can occur acutely or many years following cataract surgery, and have been described in lenses placed in the capsular bag, sulcus, or posterior to the iris with fixation sutures. None of the previously reported cases have involved a negative diopter power lens. We describe a case of spontaneous disinsertion of a haptic from a 3-piece iris-fixated IOL in a patient with pathologic myopia. To our knowledge, this is the second such case involving an iris-fixated lens, and the first case implicating a lens with negative dioptric power. Case report A 39-year-old man with a history of pathologic myopia, amblyopia, and trauma of the right eye was referred for a posteriorly dislocated crystalline lens. Medical history was significant for hypertension, hypercholesterolemia, and insulin-dependent diabetes mellitus. On exam, the patient had a proptotic right globe due to axial myopia. Motility testing revealed an intermittent exotropia of the right eye. Visual acuity was counting fingers in the right eye (improving to 20/300 on potential acuity meter testing) and 20/30 in the left eye. Intraocular pressure (IOP) was 18 mm Hg in both eyes. The right eye demonstrated a completely dislocated crystalline lens into the vitreous cavity, iridodonesis, and vitreous in the anterior chamber. The cornea was clear. Fundus exam revealed mild non-proliferative diabetic retinopathy in both eyes. No posterior staphyloma was noted. Axial length was 33.45 mm and 23.21 mm in the right and left eyes, respectively. Various treatment options were discussed including observation due to limited visual prognosis, contact lens use, or pars planavitrectomy and lensectomy with possible concurrent secondary IOL insertion. The patient was advised to address the dislocated lens to prevent retinal or ocular complications with recommendation to leave the eye aphakic and use a contact lens postoperatively. The patient adamantly refused use of contact lens and requested surgical implantation of an IOL. Selection of an IOL was limited by the need for a negative powered lens calculated by biometry. The patient underwent uncomplicated combined pars plana vitrectomy, pars plana lensectomy, and implantation of an iris-fixated 3-piece acrylic posterior chamber IOL (-5.0 diopter, MA60MA, Alcon Surgical). He did well in the early post-operative period other than requiring medical management of temporary IOP spike. The IOL was stable and centered. The patient was then lost to follow-up until presenting 11 months later with worsening vision in the right eye. Examination noted complete disinsertion of the superior haptic from the optic junction with the superior haptic still secured to the iris via prolene suture (Figure 1). The remaining optic and inferior haptic were dislocated into the vitreous cavity. The intact inferior prolene suture was still visible in the iris. The patient denied any recent trauma. IOL removal was recommended at that time, but the patient was again lost to followup. Correspondence to: Daniel P. Greene, MD, Richmond Eye Associates, 4600 Cox Road, Suite 120, Glen Allen, VA 23060, USA, Tel: 804-270-0330; E-mail: [email protected]